New-MailUser on different exchange server

I work in an environment with multiple domains, and 2 separate Exchange servers. Long story short, I need to run New-MailUser from domain1 powershell and specify/connect to the exchange server in domain2 for the new mail user creation. I’ve googled until my proverbial eyes bled and can’t seem to implement any of the suggestions.

Can anyone please help??

Have you looked into setting up a trust between the two domains?